Transcriptional Activators Enhance Polyadenylation of mRNA Precursors
نویسندگان
چکیده
منابع مشابه
Crystal structure of murine CstF-77: dimeric association and implications for polyadenylation of mRNA precursors.
Cleavage stimulation factor (CstF) is a heterotrimeric protein complex essential for polyadenylation of mRNA precursors. The 77 kDa subunit, CstF-77, is known to mediate interactions with the other two subunits of CstF as well as with other components of the polyadenylation machinery. We report here the crystal structure of the HAT (half a TPR) domain of murine CstF-77, as well as its C-termina...
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ژورنال
عنوان ژورنال: Molecular Cell
سال: 2011
ISSN: 1097-2765
DOI: 10.1016/j.molcel.2011.01.022